Jimmy Holder, MD, PhD
LabJan and Dan Duncan Neurological Research Institute1250 Moursund St., Suite 1350Houston, Texas 77030United States
- Texas Children’s Hospital, Clinical Care Center (Clinic)
- 6701 Fannin St. Ste 1250Houston, Texas 77030United States832-822-1750
- Jan and Dan Duncan Neurological Research Institute1250 Moursund St., Suite 1350Houston, Texas 77030United Statesholder@bcm.edu
Jacques L. Michaud , M.D.
Brain and Child Development
CHUSJ – Centre de Recherche
514 345-4931 #4727
Gavin Rambaugh, PhD
Seth Grant, PhD
G2C::Genes to Cognition
Centre for Clinical Brain Sciences
The long-term aim is to understand the fundamental mechanisms of behaviour and how these mechanisms are involved in brain disease.
The research has focussed on the study of genes and proteins that control the synapses between nerve cells. Multiprotein machines comprising many different protein components are responsible for basic innate and learned behaviours and dysfunction in many brain diseases.
Recent work shows that these mechanisms are conserved between mice and humans opening new avenues for diagnosis and therapeutic discoveries. The Genes to Cognition programme has generated a large amount of data and tools that are freely available