Bridge the Gap – SYNGAP – Education and Research Foundation

Jimmy Holder, MD, PhD

Addresses:

Lab

Jan and Dan Duncan Neurological Research Institute1250 Moursund St., Suite 1350Houston, Texas 77030United States

 

Texas Children’s Hospital, Clinical Care Center (Clinic)
6701 Fannin St. Ste 1250Houston, Texas 77030United States832-822-1750
Office
Jan and Dan Duncan Neurological Research Institute1250 Moursund St., Suite 1350Houston, Texas 77030United States
Jacques L. Michaud , M.D.
RESEARCH AXIS

Brain and Child Development

RESEARCH THEME

Neurodevelopmental diseases

ADDRESS

CHUSJ – Centre de Recherche

PHONE

514 345-4931 #4727

Gavin Rambaugh, PhD

The Contribution of Synaptic Plasticity to Memory, Cognition and Disease

The Rumbaugh Lab

Department of Neuroscience

The Scripps Research Institute

130 Scripps Way

Jupiter, FL 33458

Seth Grant, PhD

Professor Seth Grant

Professor of Molecular Neuroscience

G2C::Genes to Cognition

Centre for Clinical Brain Sciences

 

 

 

Research summary

The long-term aim is to understand the fundamental mechanisms of behaviour and how these mechanisms are involved in brain disease.

The research has focussed on the study of genes and proteins that control the synapses between nerve cells. Multiprotein machines comprising many different protein components are responsible for basic innate and learned behaviours and dysfunction in many brain diseases.

Recent work shows that these mechanisms are conserved between mice and humans opening new avenues for diagnosis and therapeutic discoveries. The Genes to Cognition programme has generated a large amount of data and tools that are freely available

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